EN
377 & Niacinamide Spot-Fading Single-Use Ampoule Essence
Quadruple Melanin Inhibitor (377 + α-Arbutin + Niacinamide + Ethyl VC) • Lightweight Fast-Absorbing BFS Ampoules (1.5ml*30)
- Quadruple Melanin Interception: Formulated with Phenylethyl Resorcinol (SymWhite 377), α-Arbutin, Niacinamide, and 3-O-Ethyl Ascorbic Acid to inhibit tyrosinase activity and fade stubborn dark spots.
- Water-Light Rapid Penetration: Ultra-fresh watery essence texture that absorbs instantly without stickiness, delivering active brightening power directly to the basal layer.
- Soothing Anti-Rebound Shield: Enriched with Glycyrrhetinic Acid and Camellia Extract to calm skin redness and prevent post-inflammatory hyperpigmentation.
- BFS Sterile Fresh-Lock: Medical-grade Blow-Fill-Seal one-step packaging eliminates oxidation and color degradation; 1.5ml precise single-use dosage.
- Turnkey Private Label Support: Factory direct MOQ from 5.000 boxes for custom branding; in-stock brand from 10 pcs; free lab formulation samples in 7–10 days.
MOQ: 5000 *Free samples can be provided
- Overview
- Recommended Products
1 Specifications & B2B Ordering Parameters
| Parameter | Standard Specification | OEM / ODM Customization |
|---|---|---|
| Product Name | 377 Whitening Single-Use Essence | Custom Brand Name, Artwork & Logo |
| Product SKU | 427436 | Custom SKU & EAN/UPC Barcode |
| Standard Spec | 1.5 ml × 30 vials / box (or 5 vials / strip) | 1.0ml / 1.2ml / 1.5ml / 2.0ml (5 / 7 / 14 / 30 vials) |
| Box Size & Weight | 9.8 × 13.1 × 8.8 cm / 0.2667 kg | Custom Rigid Box, Slide Box, Folding Carton |
| Master Carton Details | 60 boxes / Carton (46.7 × 44.5 × 42.0 cm, ~16.91 kg) | Reinforced Export Carton with Shipping Marks |
| Key Actives | 377 (Phenylethyl Resorcinol), α-Arbutin, Niacinamide, 3-O-Ethyl Ascorbic Acid, Glycyrrhetinic Acid, Camellia Extract, Sodium Hyaluronate | Custom Active Concentrations & Botanicals |
| Formula Texture | Water-Light Fluid Essence (Rapid Basal Layer Absorption) | Fresh watery texture, zero greasy residue |
| MOQ | • In-stock Brand: from 10 pcs • Private Label / OEM: 5,000 boxes |
Tiered volume contract pricing |
| Lead Time | • Samples: 7–10 working days • Mass Production: 28–45 days |
Free Formula Samples Available |
| Certifications | GMPC (US FDA), ISO 22716, MSDS, COA, Stability Report | Full export compliance & safety testing |
2 Turnkey Manufacturing & Formulation Advantages
Dual-Stage RO Purified Water Base
Produced with secondary reverse osmosis purified water conforming to ISO 22716 standards, ensuring zero mineral ions and protecting active 377 from catalytic oxidation.
100,000-Grade Aseptic BFS Cleanroom
12 automated production lines delivering 80,000–90,000 ampoule vials daily with high-speed automated Blow-Fill-Seal molding and zero chemical preservatives.
Global Export Compliance Dossiers
Supported by 40+ R&D scientists with full 377 regulatory dossiers, MSDS, COA, Stability Reports, and factory GMPC (US FDA) / ISO 22716 certifications for seamless customs clearance.
3 Frequently Asked Questions (FAQ)
Q1: How does this water-based 377 formula differ from emulsion/lotion types in clinical application?
A: This formula features a lightweight, water-soluble micro-molecular vehicle designed for rapid transdermal penetration into the basal epidermal layer where melanocytes reside. It absorbs in seconds with zero tackiness, making it the ideal daily brightening step across hot/humid climates, oily/combination skin types, and for layering beneath sunscreen or makeup.
Q2: How does your factory guarantee 377 active stability and prevent formula discoloration?
A: Standalone 377 (Phenylethyl Resorcinol) is susceptible to photo-oxidation in traditional dropper bottles. We resolve this through pharmaceutical-grade Blow-Fill-Seal (BFS) aseptic technology. Formed, filled, and sealed in an airtight cycle under 200°C sterile conditions, the formula remains completely isolated from ambient air, oxygen, and UV light, ensuring full active potency and zero yellowing throughout a 36-month shelf life.
Q3: How do you prevent skin irritation and rebound darkening during intensive spot-fading?
A: High active concentrations without soothing buffers can trigger micro-inflammation. We formulate 377 within international cosmetic safety limits and synergize it with Glycyrrhetinic Acid and Camellia Sinensis Extract. This dual soothing barrier neutralizes inflammatory pathways, ensuring gentle spot-fading suitable for all skin tones and sensitive skin without peeling or burning.
Q4: How do you guarantee zero leakage and carton integrity during international shipping?
A: Our ampoules are manufactured from medical-grade, shatterproof PP material, undergoing 100% negative pressure vacuum leak testing to withstand high-altitude air pressure variations. 60 boxes are packed into heavy-duty 5-ply K=K corrugated export master cartons (46.7 × 44.5 × 42.0 cm, ~16.91 kg) with inner PE moisture liners and corner protectors to ensure zero crushing during sea freight transit.
Q5: What is the MOQ, sample turnaround, and mass production schedule for OEM/ODM?
A: For custom private label branding, our MOQ is 5,000 boxes (or from 10 pcs for in-stock brand inventory). We provide free formula lab samples within 7–10 business days. Commercial mass production takes 28–45 business days after packaging artwork and formulation approval.
Q6: Do you supply export compliance documents for customs clearance?
A: Yes. All shipments include complete regulatory dossiers: MSDS (Material Safety Data Sheet), COA (Certificate of Analysis), Stability Testing Reports, Non-Dangerous Goods shipping declarations for sea/air freight, and factory GMPC (US FDA) / ISO 22716 certifications.
Ready to Launch Your Custom 377 Ampoule Skincare Line?
Contact our factory B2B engineering team today for immediate tiered wholesale pricing, packaging catalogs, and free custom lab samples.
